GastroIntestinal Drugs

PASPERAN

Description: PHARMACEUTICAL  EFFECTS: Gastro-intestinal Action:PASPERAN seems to sensitise tissues to the action of acetylcholine. PASPERAN increases the number, strength and activity of gastric antral contractions and also producing an increase in the strength of duodenal contractions.These changes increase the speed of gastric emptying and reduce reflux from the duodenum and the stomach into the oesophagus. Which has …

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LOTAN

Description: CLINICAL PHARMACOLOGY Diphenoxylate is rapidly and extensively metabolized in man by ester hydrolysis to diphenoxylic acid (difenoxine), which is the major metabolite in the blood and biologically active. An average of 14% of the drug plus its metabolites were excreted in the urine and 49% in the faeces over a 4-day period. Urinary excretion …

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